Plenty. Some standard combos would include: (1) Flue cured mixed with Latakia and Turkish leaf, (2) Flue Cured mixed with Perique, (3) Straight Burley, (4) Straight Turkish. The combinations are almost endless. A blend that contains Virginia Brightleaf, Latakia and Prilep is going to taste vastly different compared to a blend that contains Virginia Brightleaf, Latakia and Samsun Maden. Replace the Samsun Maden with another Turkish such as Bucak and you will change the flavor again.
My staples for pipes tobacco are: Little Dutch, Samsun Maden, Bucak, Tekekoy, Virginia Brightleaf, Perique and Latakia.