Wonder if it might be better to plant tobacco elsewhere next spring. Maybe let the soil in the garden heal for a year and cover it with a decent layer of ash and compost this fall followed by a legume cover crop next spring that gets mixed back in. Or do it the easy way like you said and get a soil analysis then ph it and some compost and fertilizer the hell out of it - the plants don't look that bad.I need to get some soil testing done. The darker coloured, larger tobacco plants on the right are in a space where there had been a steel shed for decades. There is a clear line in both rows, even with that 4x4 post. I do recall it being easier to dig than the left which had been used as a garden.
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I've had my vegetable garden in the same spot for 17 years. I've tried growing plants in other locations in the yard but they all get the same disease anyway (the joys of gardening in a swamp). The big difference I notice usually comes down to how much new compost/soil and wood ash I add to the raised bed garden and if I till it in or not. The more compost the better seems to be the trend with mine.