I'm not sure what you are talking about. Green, uncured leaf? Fully cured leaf? Finished leaf? Manufactured tobacco product? Sufficient ethanol on the surface of a green tobacco leaf will ruin it. I am unaware of any use of ethanol in tobacco manufacturing, other than occasionally as a vehicle for adding artificial flavors.see how anti freeze effect the tobacco
And you should be clear about this. Automotive antifreeze is ethylene glycol, and will destroy your kidneys and kill you. Just about any chemical added to water will lower the freezing point.
Bob