Welcome to the forum.
Your leaves are finished color curing. I would dry them down immediately. I don't see anything that would cause me to not smoke this leaf, though I would avoid using it as chew or cigar
wrapper, since there is evidence of mold. The close-ups below are from your first image:
Fuzzy mold mycelia on the stem.
Since the cured stem remains more hygroscopic (moisture holding) than the cured lamina, some small amount of mold on the stem is common, but can spread. This leaf needs to be dried.
"Coffee-stain" effect.
"Coffee-stain" effect is the migration toward the perimeter of coffee particles in a spill of coffee. Here, I'm suggesting that this perimeter coloration is from something that "grew" outward from an initial point, or an injured area of the leaf that has necrosed from the center of previously injured leaf lamina. Might be mold, or might be any one of a number of other causes (from the field or from the shed).
Likely Aspergillus niger.
No question, this is molded here.
Aspergillus mold produces aflatoxin that is hepatotoxic (toasts your liver). Studies have shown that aflatoxin is
not present in the smoke of combusted tobacco, but it is present, and can be absorbed into your body, if you suck on the unburned leaf (smokeless, or used as a cigar wrapper).
Bob