So I was going to mention what plants do well with tight spacing. I liked the african red, out of the cluster grow I had about 5 main stalks that took of growing out of a 1'x2' area. they grew to be about 8' tall and the most I harvested off of one plant was around 18 leaves. the biggist leaf was about 22" long by 18" wide, it was big.
Today Iharvested the Lemon Bright and all I can say is WOW! 7-8 main stalks grew out of a 1'x2' area and the leaf on them were more numerous and bigger. In fact, I may need two sticks to string up that variety. Of the fluecured varieties, this one was by far the largest producer and the better quality leaf too that tends to air cure brighter then other varieties.
I should mention that they were planted not to far from the compost pile and I'm sure that that had helped them grow the way they did. In light of that, I would say that treating a trench much like Po Green did in his compost holes and making a good mound compost rich soil, I believe you could easily have an inrow planting of 1' apart and still get super sized plants.
Mcnair was another good one that handled tight spacing well. Interesting is that between lemon bright, African red, and Mcnair have similar leaf and plant style of growth and are very different then other virginia types.